Sermorelin
A 29-amino-acid GHRH analogue used since the 1990s to assess and stimulate pituitary GH production.
How it works
Mimics native GHRH and binds the GHRH-R, restoring physiologic GH pulses without desensitising the pituitary.
Reported benefits
- Increases endogenous GH and IGF-1 over weeks of therapy
- Used historically for pediatric GH deficiency diagnostics
- May improve sleep quality
Dosage & administration
Research range: 200-500 mcg subcutaneously at bedtime.
Dosing information is summarised from published clinical and pre-clinical literature for research purposes only and does not constitute medical advice.
Clinical & pre-clinical evidence
Sermorelin in adult GH deficiency
Pediatric Research · 1994
Restored GH pulsatility in subjects with hypothalamic dysfunction.
Safety & warnings
- Possible injection-site reactions
- Avoid in malignancy
For research use. Consult a licensed clinician before any human application. Not for use in pregnancy, lactation, or active malignancy without specialist supervision.
Available presentations
5 mg
SMO5
Box of 10 · $210
Single vial · $420
10 mg
SMO10
Box of 10 · $426
Single vial · $852
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