BPC 157
A pentadecapeptide derived from human gastric juice with broad regenerative effects in pre-clinical models.

How it works
Body Protection Compound 157 upregulates the VEGFR2-eNOS pathway, accelerates angiogenesis, modulates NO signalling, and influences dopaminergic and serotoninergic systems. It also stimulates expression of growth-hormone receptor in tendon and ligament fibroblasts.
Reported benefits
- Accelerated tendon-to-bone and tendon-to-tendon healing in animal models
- Protection of the gastric and intestinal mucosa
- Improved blood-vessel formation around injured tissue
- Modulation of inflammatory cytokines
Dosage & administration
Research range: 200-500 mcg subcutaneously near the area of interest, 1-2x daily for 4-6 weeks. Oral arginate salt has also been studied.
Dosing information is summarised from published clinical and pre-clinical literature for research purposes only and does not constitute medical advice.
Clinical & pre-clinical evidence
BPC 157 and the central nervous system
Frontiers in Pharmacology · 2022
Review of >100 pre-clinical studies showing systemic regenerative effects.
BPC 157 accelerates Achilles tendon healing in rats
Journal of Orthopaedic Research · 2010
Significantly improved tensile strength and collagen organisation.
Safety & warnings
- No serious adverse events reported in published animal work
- Limited controlled human trials
- Avoid concurrent use with active malignancy due to pro-angiogenic effect
For research use. Consult a licensed clinician before any human application. Not for use in pregnancy, lactation, or active malignancy without specialist supervision.
Available presentations
5 mg
BC5
Box of 10 · $144
Single vial · $288
10 mg
BC10
Box of 10 · $210
Single vial · $420
Related guides

TB500 (Thymosin B4 Acetate)
A synthetic fragment of thymosin β-4 that promotes cell migration, angiogenesis, and tissue repair.

BPC + TB Blend
Combined BPC 157 and TB500 blend used in recovery protocols to overlap angiogenic and cytoskeletal effects.

Klow (TB10 + BPC10 + GHK50 + KPV10)
Quad blend combining TB500, BPC 157, GHK-Cu, and KPV for systemic regeneration and anti-inflammatory effects.
