NAD+
Nicotinamide adenine dinucleotide, the universal coenzyme central to redox metabolism and sirtuin signalling.
How it works
Substrate for SIRT1-7, CD38, and PARP enzymes; central to oxidative phosphorylation. Cellular NAD+ declines with age.
Reported benefits
- Restoration of cellular NAD+ pools
- Improved mitochondrial function in aged cells
- Subjective energy and clarity reports
Dosage & administration
Research range: 100-500 mg subcutaneously 2-3x weekly; slow IV infusion in clinical settings.
Dosing information is summarised from published clinical and pre-clinical literature for research purposes only and does not constitute medical advice.
Clinical & pre-clinical evidence
NAD+ precursors and metabolic health
Nature Reviews Drug Discovery · 2020
Boosting NAD+ improves multiple aging biomarkers in pre-clinical and early clinical work.
Safety & warnings
- IV push must be slow — rapid infusion causes flushing, nausea, chest tightness
- Generally well tolerated SC
For research use. Consult a licensed clinician before any human application. Not for use in pregnancy, lactation, or active malignancy without specialist supervision.
Available presentations
100 mg
NJ100
Box of 10 · $135
Single vial · $270
500 mg
NJ500
Box of 10 · $270
Single vial · $540
1000 mg
NJ1000
Box of 10 · $507
Single vial · $1,014
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