Epitalon
A synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from epithalamin, studied for telomerase activation and circadian benefits.

How it works
Upregulates pineal telomerase expression in cultured human cells and restores melatonin rhythm in elderly rats.
Reported benefits
- Increased telomerase activity in human cell lines
- Improved sleep-wake regularity in elderly cohorts
- Reduced mortality in long-running Russian aging studies (controversial)
Dosage & administration
Research range: 5-10 mg subcutaneously daily for 10-20 days, repeated 1-2 cycles per year.
Dosing information is summarised from published clinical and pre-clinical literature for research purposes only and does not constitute medical advice.
Clinical & pre-clinical evidence
Epitalon and telomerase activity in human cells
Bulletin of Experimental Biology and Medicine · 2003
Demonstrated telomerase induction and telomere elongation in vitro.
Safety & warnings
- No serious adverse events reported
- Long-term human safety still limited
For research use. Consult a licensed clinician before any human application. Not for use in pregnancy, lactation, or active malignancy without specialist supervision.
Available presentations
10 mg
ET10
Box of 10 · $105
Single vial · $210
50 mg
ET50
Box of 10 · $486
Single vial · $972
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