5-amino-1mq
An NNMT inhibitor analogue investigated for metabolic and muscle benefits.
How it works
Like 10-amino-1mq, blocks NNMT to elevate intracellular NAD+ and SAM. Particularly studied in skeletal-muscle aging.
Reported benefits
- Improved muscle stem-cell function in aged rodents
- Reduced adiposity in DIO mice
- Increased exercise capacity in animal studies
Dosage & administration
Research range: 50-150 mg/day reported in pre-clinical literature.
Dosing information is summarised from published clinical and pre-clinical literature for research purposes only and does not constitute medical advice.
Clinical & pre-clinical evidence
NNMT inhibition rejuvenates aged muscle stem cells
Cell Reports · 2020
Improved myogenic capacity of aged satellite cells.
Safety & warnings
- Pre-clinical only
- No human safety data
For research use. Consult a licensed clinician before any human application. Not for use in pregnancy, lactation, or active malignancy without specialist supervision.
Available presentations
5 mg
5AM
Box of 10 · $330
Single vial · $660
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